Sneak Peek #46: Big step toward targeted molecular therapies for cancer

Two new studies represent a big step toward developing innovative molecular therapies capable of disrupting the uncontrollable growth of cancers at their roots.

In a pair of papers recently published in Nature, a team of scientists led by Harvard’s Department of Chemistry and Chemical Biology (CCB) has demonstrated how both small molecules and genetic mutations can alter the same critical protein interactions in cancer cells. These studies provide insights into two areas: discovering new “molecular glues” and understanding the impact of genetic mutations within cancer cells, setting the stage for therapeutic approaches.